A meta analysis reviewed 27 studies conducted on depression and diabetes and found a significant relationship between depression and diabetic complications (Groot, 2001). All the studies reviewed found that depression can increase the risk of diabetic neuropathy, nephropathy and vascular complications.
A long term prospective study was conducted on a cohort of 6095 patients who did not have a history of stroke. A positive correlation was found between depression and stroke and depression was found to be an independent predictor of stroke in both genders and all ethnicities (Jonas, 2000).
Only a few studies have been conducted to see the relationship of depression with multiple sclerosis. A meta analysis found that patients with multiple sclerosis are more depressed than control groups (patients without multiple sclerosis) (Schubert, 1993).
The WHO survey clearly highlights the burden of depression and its association with other diseases. This survey was conducted over 60 countries of the world and it was found that prevalence of depression with other medical illnesses was significantly higher than the prevalence of depression in the absence of any other medical illness. It was also found that depression had the greatest impact on health scores as compared to other chronic diseases like asthma, diabetes, arthritis, cardiovascular diseases, etc.
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