A standard protocol will be followed to assess all the patients in order to minimize errors and variability of results. Before the start of the study, a two day workshop will be conducted to orient all the researchers to the study protocol and methodology.
At the end of the study, data will be organized properly and data analysis will be done using SPSS (version 16.0). All the outcome measures in the two groups will be compared to conclude whether intravaginal estrogen is safer compared to oral estrogen or not. Chi-squared test will be used to compare categorical variable and student t-test will be used to compare continuous variables.
All patients will be well informed about the risks and benefits of participation in the study. Written informed consent will be taken from the participants and they will have the right to withdraw from the study at any time. All the information obtained from the participants will remain confidential and anonymity will be maintained at all times.
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